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Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 415-420 doi: 10.1007/s11684-009-0072-z

Abstract: aim of this study was to investigate the inhibitory effects of recombinant adenovirus vector carrying tissueinhibitor of metalloproteinase-3 (RAdTIMP-3) against degeneration of rabbit intervertebral disc.According to Thompson’s criteria, the degeneration of groups 3, 4, and 5, especially group 3, wasRT-PCR revealed that the expression of TIMP-3 in groups 3, 4, and 5, especially in group 3, was significantlyTIMP-3 staining exhibited an obvious increase of positive-staining rate in groups 3, 4, and 5 as compared

Keywords: tissue inhibitor of metalloproteinase-3     intervertebral disc     rabbit     gene therapy    

Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 100-107 doi: 10.1007/s11684-009-0013-x

Abstract: The expression of integrin-β1, tumor growth factor-β (TGF-β) and tissue inhibitor of metalloproteinase

Keywords: liver fibrosis     integrin-β1     resveratrol     tumor growth factor-β     tissue inhibitor of metalloproteinase-1    

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract:

Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulation

Keywords: arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: tissue with three-dimensional (3D) structural integrity and cellular-function regulation.substitutes mediate cell–matrix interactions to prompt stem-cell proliferation and differentiation for 3DCellular ECM improves 3D culture development in vitro and tissue remodeling during wound healingGaining better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstructionsupplements used in cell propagation and differentiation for 3D tissue culture in vitro are discussed

Keywords: decellularized extracellular matrix     3D culture     organoids     tissue repair    

Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissue

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3,   Pages 339-347 doi: 10.1007/s11705-012-1209-1

Abstract: Dextran-hyaluronate (Dex-HA) based supermacroporous cryogel scaffolds for soft tissue engineering wereThe culture of 3T3-L1 preadipocyte within the scaffold was investigated and observed by SEM.indicating the Dex-HA cryogel scaffold could be a promising porous biomaterial for applications in tissue

Keywords: cryogel scaffold     tissue engineering     dextran     hyaluronate     3T3-L1 preadipocyte    

Effects of phosphatidylinositol 3-kinase inhibitor on human cervical carcinoma cells

Yuan ZHANG MD , Xiaoyan ZHANG MM , Yanhui LI MM , Xuan DU MM , Zehua WANG MD, PhD , Hongbo WANG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 341-346 doi: 10.1007/s11684-009-0067-9

Abstract: Phosphatidylinositol 3-kinase (PI3K) is a crucial cell survival pathway implicated in tumorigenesis becauseThis study was to investigate the regulation of proliferation and apoptosis by LY294002, an inhibitorof PI3K in cervical cancer cells and the expression of FLICE-like inhibitory protein (c-FLIP) .Cell viability was measured by 3-(4,5)-dimethylthiazol(-2-y1)-3,5-di-phenyltetrazoliumbromide (MTT) assayThese results suggested that the PI3K/Akt signal pathway might be involved in the regulation of cell

Keywords: human cervical cancer cells     apoptosis     phosphatidylinositol 3-kinase (PI3K)/Akt     FLICE-like inhibitory    

A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

Engineering 2017, Volume 3, Issue 5,   Pages 653-662 doi: 10.1016/J.ENG.2017.05.013

Abstract: Such new applications demand high-fidelity, patient-specific, tissue-mimicking medical phantoms thatWith the rapid advancement of three-dimensional (3D) printing and 3D bioprinting technologies, many researchersThis paper reviews the applications of these 3D printing and 3D bioprinting technologies for the fabricationThis review specifically discusses the state of the art along with new developments and trends in 3Dprinted functional medical phantoms (i.e., tissue-mimicking medical phantoms, radiologically relevant

Keywords: 3D printing     3D bioprinting     Medical phantom     Regenerated tissue/organ     Scaffold    

Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Frontiers of Mechanical Engineering 2018, Volume 13, Issue 1,   Pages 107-119 doi: 10.1007/s11465-018-0496-8

Abstract:

Tissue engineering (TE) is an integrated discipline that involves engineering and natural sciencesurgical treatments have been reported to have side effects on patients caused by organ necrosis and tissue

Keywords: tissue engineering     scaffolds     electrospinning     3D printing     molding techniques     conventional methods    

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 72-76 doi: 10.1007/s11684-014-0347-x

Abstract: Any imbalance between the matrix metalloproteinases (MMPs) secreted by neutrophils and tissue inhibitorsinitiates the destruction of collagen in gum tissue, leading to chronic periodontitis.Around 3 ml of unstimulated and whole expectorated saliva was collected for MMP-8 estimation by ELISA

Keywords: matrix metalloproteinase-8     chronic periodontitis     pocket probing depth     clinical attachment level     gingival    

3D Photo-Fabrication for Tissue Engineering and Drug Delivery Review

Rúben F. Pereira, Paulo J. Bártolo

Engineering 2015, Volume 1, Issue 1,   Pages 90-112 doi: 10.15302/J-ENG-2015015

Abstract:

The most promising strategies in tissue engineering involve the integration of a triad of biomaterialssynthetic environments that closely mimic the healing milieu present in human tissues, and that stimulate tissuePhoto-fabrication techniques have already been used to generate 3D environments with precise architecturestherapeutic molecules can be included in the initial hydrogel precursor solution, and processed into 3DThis paper focuses on the use of 3D photo-fabrication techniques to produce advanced constructs for tissue

Keywords: 3D photo-fabrication     biomaterials     tissue engineering     drug delivery    

Visible Light-Induced 3D Bioprinting Technologies and Corresponding Bioink Materials for Tissue Engineering Review

Zizhuo Zheng, David Eglin, Mauro Alini, Geoff R. Richards, Ling Qin, Yuxiao Lai

Engineering 2021, Volume 7, Issue 7,   Pages 966-978 doi: 10.1016/j.eng.2020.05.021

Abstract:

Three-dimensional (3D) bioprinting based on traditional 3D printing is an emerging technology thatis used to precisely assemble biocompatible materials and cells or bioactive factors into advanced tissuetechnology, particularly photo-cured bioprinting strategies, plays an important role in the field of tissueThe successful implementation of 3D bioprinting
is based on the properties of photopolymerizedWe also discuss existing challenges and prospects of visible light-induced 3D bioprinting devices and

Keywords: Medical additive manufacturing     Bioink     Tissue engineering     3D bioprinting    

Three-dimensional reconstruction of light microscopy image sections: present and future

Yuzhen Wang,Rui Xu,Gaoxing Luo,Jun Wu

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 30-45 doi: 10.1007/s11684-014-0337-z

Abstract: in human tissue.Computer technologies can produce 3D representations of interesting human tissue and organs that havebeen serial-sectioned, dyed or stained, imaged, and segmented for 3D visualization. 3D reconstructionalso has great potential in the fields of tissue engineering and 3D printing.This article outlines the most common methods for 3D tissue section reconstruction.

Keywords: microtomy     3D imaging     computer-assisted image processing     3D printing     tissue scaffold    

Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: non-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissueThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords: thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophic hormone     prolactin    

Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract: addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissueSeveral important aspects related to tissue engineered nerves, including the theory on their constructionFurthermore, potential research directions for the future development of neural tissue engineering are

Keywords: nerve injury     tissue engineering     nerve grafts    

Design and 3D Printing of Scaffolds and Tissues Review

Jia An, Joanne Ee Mei Teoh, Ratima Suntornnond, Chee Kai Chua

Engineering 2015, Volume 1, Issue 2,   Pages 261-268 doi: 10.15302/J-ENG-2015061

Abstract:

A growing number of three-dimensional (3D)-printing processes have been applied to tissue engineeringThis paper presents a state-of-the-art study of 3D-printing technologies for tissue-engineering applications, with particular focus on the development of a computer-aided scaffold design system; the direct 3Dmanufacturing of scaffolds, with both micro and macro features; the development of a bioreactor; and 3Dmethodologies for tissue engineering.

Keywords: rapid prototyping     3D printing     additive manufacturing     tissue engineering     bioprinting    

Title Author Date Type Operation

Adenovirus-mediated tissue inhibitor of metalloproteinase-3 gene transfection inhibits rabbit intervertebral

Xudong YU MM, Zengwu SHAO MD, Liming XIONG MD, Weiwei XU MM, Hezhong WANG MM, Huifa XU MM,

Journal Article

Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

Decellularized extracellular matrix mediates tissue construction and regeneration

Journal Article

Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissue

Dongjiao ZHOU, Shaochuan SHEN, Junxian YUN, Kejian YAO, Dong-Qiang LIN

Journal Article

Effects of phosphatidylinositol 3-kinase inhibitor on human cervical carcinoma cells

Yuan ZHANG MD , Xiaoyan ZHANG MM , Yanhui LI MM , Xuan DU MM , Zehua WANG MD, PhD , Hongbo WANG MD ,

Journal Article

A Review on the 3D Printing of Functional Structures for Medical Phantoms and Regenerated Tissue and

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

Journal Article

Fabrication of scaffolds in tissue engineering: A review

Peng ZHAO, Haibing GU, Haoyang MI, Chengchen RAO, Jianzhong FU, Lih-sheng TURNG

Journal Article

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Journal Article

3D Photo-Fabrication for Tissue Engineering and Drug Delivery

Rúben F. Pereira, Paulo J. Bártolo

Journal Article

Visible Light-Induced 3D Bioprinting Technologies and Corresponding Bioink Materials for Tissue Engineering

Zizhuo Zheng, David Eglin, Mauro Alini, Geoff R. Richards, Ling Qin, Yuxiao Lai

Journal Article

Three-dimensional reconstruction of light microscopy image sections: present and future

Yuzhen Wang,Rui Xu,Gaoxing Luo,Jun Wu

Journal Article

Atypical pituitary hormone–target tissue axis

Journal Article

Progress and perspectives of neural tissue engineering

Xiaosong Gu

Journal Article

Design and 3D Printing of Scaffolds and Tissues

Jia An, Joanne Ee Mei Teoh, Ratima Suntornnond, Chee Kai Chua

Journal Article